MAP2K2 — Abundance

🧬 View Structure

59 interactions

DMS Score Heatmap Scroll horizontally • click a column to see interactions • ■ purple strip = interface positions

PKc_MAP2K2 A V I L G F Y W C M P S T N Q D E H K R * 20 40 60 80 100 120 140 160 180 200 220 240 260 280 300 320 340 360 380 0.11 1.00 1.50
Click a position to see interactions — ■ orange strip marks interface positions (darker = more interactions)

Significant Interactions

Interactor Predictor Log FC p-value (FDR) Cliff's Delta AUROC Unique Pos. % Unique # Interface Clashes Structure
KSR2 Predictomes 0.036 1.50e-01 0.057 0.529 — — 15 0 View 3D
MAP4K5 Predictomes 0.019 8.78e-01 -0.008 0.496 — — 9 0 View 3D
MAP3K7 Predictomes 0.043 5.47e-02 0.071 0.535 — — 18 0 View 3D
MAPK1 Predictomes 0.047 1.99e-02 0.098 0.549 — — 13 0 View 3D
BRAF Predictomes 0.048 2.94e-02 0.091 0.546 — — 13 0 View 3D
MAPK3 Predictomes 0.042 4.38e-02 0.085 0.543 — — 13 0 View 3D
KSR2 Predictomes 0.027 5.30e-01 0.027 0.513 — — 14 0 View 3D
WDR83 Predictomes 0.001 3.37e-01 -0.044 0.478 — — 11 0 View 3D
ARAF Predictomes 0.039 1.16e-01 0.063 0.531 — — 15 0 View 3D
ARAF Predictomes 0.033 3.06e-01 0.046 0.523 — — 12 0 View 3D
MAP2K1 Predictomes 0.033 3.90e-01 0.039 0.519 — — 12 0 View 3D
STK26 Predictomes 0.035 2.23e-01 0.056 0.528 — — 11 0 View 3D
MAPK8 Predictomes 0.018 8.98e-01 0.007 0.504 — — 8 0 View 3D
MAP2K1 Predictomes 0.031 4.67e-01 0.038 0.519 — — 9 0 View 3D
RAF1 Predictomes 0.050 1.13e-02 0.098 0.549 — — 15 0 View 3D
STK26 Predictomes 0.040 8.19e-02 0.067 0.533 — — 16 0 View 3D
MAP3K7 Predictomes 0.045 8.61e-02 0.068 0.534 — — 15 0 View 3D
MAP2K5 Predictomes 0.081 2.15e-02 0.190 0.595 — — 3 0 View 3D
MAP2K3 Predictomes 0.013 7.11e-01 -0.024 0.488 — — 6 0 View 3D
ARAF Predictomes 0.041 7.44e-02 0.071 0.535 — — 15 0 View 3D
RAF1 Predictomes 0.039 8.40e-02 0.067 0.533 — — 16 0 View 3D
MAP2K3 Predictomes 0.027 6.97e-01 0.022 0.511 — — 8 0 View 3D
MAP4K5 Predictomes 0.044 1.85e-01 0.059 0.530 — — 12 0 View 3D
STK26 Predictomes 0.013 8.16e-01 -0.013 0.493 — — 8 0 View 3D
RAF1 Predictomes 0.031 3.93e-01 0.036 0.518 — — 14 0 View 3D
WDR83 Predictomes 0.003 4.00e-01 -0.039 0.480 — — 11 0 View 3D
MAP2K5 Predictomes 0.064 1.77e-01 0.114 0.557 — — 3 0 View 3D
KSR1 Predictomes 0.046 4.50e-02 0.075 0.538 — — 17 0 View 3D
WDR83 Predictomes 0.001 4.04e-01 -0.041 0.480 — — 10 0 View 3D
MAP4K5 Predictomes 0.030 5.52e-01 0.030 0.515 — — 10 0 View 3D
MOS Predictomes 0.030 5.30e-01 0.030 0.515 — — 11 0 View 3D
MAPK3 Predictomes 0.039 1.32e-01 0.077 0.538 — — 9 0 View 3D
KSR1 Predictomes 0.037 1.55e-01 0.054 0.527 — — 17 0 View 3D
MOS Predictomes 0.039 1.28e-01 0.070 0.535 — — 11 0 View 3D
MOS Predictomes 0.031 5.02e-01 0.032 0.516 — — 11 0 View 3D
BRAF Predictomes 0.055 6.44e-03 0.112 0.556 — — 13 0 View 3D
MAPK1 Predictomes 0.030 2.95e-01 0.049 0.524 — — 11 0 View 3D
MAP2K1 Predictomes 0.005 6.39e-01 -0.017 0.491 — — 21 0 View 3D
MAP3K7 Predictomes 0.047 1.42e-02 0.087 0.543 — — 19 0 View 3D
BRAF Predictomes 0.049 3.31e-02 0.089 0.544 — — 13 0 View 3D
MAPK3 Predictomes 0.031 2.84e-01 0.050 0.525 — — 11 0 View 3D
MAPK1 Predictomes 0.030 3.24e-01 0.048 0.524 — — 10 0 View 3D
KSR2 Predictomes 0.024 6.60e-01 0.018 0.509 — — 15 0 View 3D
MAP2K3 Predictomes 0.026 7.42e-01 0.020 0.510 — — 7 0 View 3D
KSR1 Predictomes 0.034 2.38e-01 0.046 0.523 — — 16 0 View 3D
BRAF Zhang_et_al 0.038 2.65e-01 0.055 0.528 — — 11 0 View 3D
MAPK1 Zhang_et_al 0.048 1.14e-01 0.101 0.551 — — 6 0 View 3D
RHOBTB2 Zhang_et_al 0.068 4.98e-02 0.147 0.574 — — 4 0 View 3D
BBS7 Zhang_et_al 0.004 5.70e-01 -0.032 0.484 — — 10 0 View 3D
ARAF Zhang_et_al 0.019 3.39e-01 0.039 0.520 — — 17 0 View 3D
MAP3K1 Zhang_et_al 0.021 8.11e-01 0.013 0.506 — — 11 0 View 3D
MAP3K2 Zhang_et_al 0.034 5.70e-01 0.040 0.520 — — 6 0 View 3D
PGRMC1 Zhang_et_al 0.037 2.62e-01 0.068 0.534 — — 7 0 View 3D
MAPK3 Zhang_et_al 0.059 1.74e-02 0.128 0.564 — — 8 0 View 3D
MAPK8 Zhang_et_al 0.002 5.85e-01 -0.026 0.487 — — 14 0 View 3D
MOS Zhang_et_al 0.044 2.02e-01 0.072 0.536 — — 8 0 View 3D
RAF1 Zhang_et_al 0.033 1.35e-01 0.058 0.529 — — 18 0 View 3D
MAP2K2 RCSB_PDB 0.048 2.71e-02 0.093 0.546 — — 13 0 View 3D
MAP2K2 RCSB_PDB 0.023 6.95e-01 0.019 0.510 — — 11 0 View 3D