KRAS — Activity

🧬 View Structure

292 interactions

DMS Score Heatmap Scroll horizontally • click a column to see interactions • ■ purple strip = interface positions

H_N_K_Ras_like A V I L G F Y W C M P S T N Q D E H K R * 20 40 60 80 100 120 140 160 180 0.10 1.00 3.43
Click a position to see interactions — ■ orange strip marks interface positions (darker = more interactions)

Significant Interactions

Interactor Predictor Log FC p-value (FDR) Cliff's Delta AUROC Unique Pos. % Unique # Interface Clashes Structure
ADGRG1 Predictomes -0.442 1.29e-16 -0.406 0.297 0 0% 9 0 View 3D
USE1 Predictomes -0.557 3.12e-12 -0.410 0.295 0 0% 6 0 View 3D
TTC4 Predictomes -0.597 7.83e-11 -0.384 0.308 0 0% 6 0 View 3D
EXOC1 Predictomes -0.699 8.96e-29 -0.571 0.214 0 0% 8 0 View 3D
NME6 Predictomes -1.386 1.36e-17 -0.690 0.155 0 0% 3 0 View 3D
IL1RAP Predictomes -1.309 1.66e-53 -0.754 0.123 0 0% 9 0 View 3D
RASGRP1 Predictomes 0.285 1.44e-10 -0.231 0.385 0 0% 23 0 View 3D
RRAS2 Predictomes -1.234 9.73e-44 -0.650 0.175 1 10% 10 0 View 3D
RASGRF1 Predictomes 0.247 4.30e-12 -0.274 0.363 0 0% 18 0 View 3D
TRIO Predictomes 0.868 2.24e-01 -0.078 0.461 0 0% 6 0 View 3D
ARHGDIA Predictomes -0.308 5.37e-12 -0.339 0.330 0 0% 9 0 View 3D
UTP6 Predictomes -0.478 1.16e-14 -0.348 0.326 0 0% 11 0 View 3D
RASGRP4 Predictomes 0.227 8.46e-16 -0.289 0.356 0 0% 23 0 View 3D
PLXNA1 Predictomes 0.387 7.24e-03 -0.126 0.437 0 0% 12 0 View 3D
TAOK3 Predictomes -0.479 8.00e-13 -0.370 0.315 0 0% 8 0 View 3D
SGSM2 Predictomes -0.014 2.13e-15 -0.340 0.330 — — 13 0 View 3D
PIK3R4 Predictomes -0.682 9.47e-37 -0.550 0.225 0 0% 12 0 View 3D
FAM91A1 Predictomes 0.254 1.55e-05 -0.222 0.389 1 11% 9 0 View 3D
PIK3CA Predictomes -0.812 4.68e-25 -0.482 0.259 0 0% 10 0 View 3D
YKT6 Predictomes -0.285 1.12e-11 -0.348 0.326 0 0% 8 0 View 3D
SIPA1L1 Predictomes -0.532 3.03e-31 -0.473 0.263 0 0% 15 0 View 3D
ATP5F1B Predictomes -0.508 1.64e-06 -0.391 0.304 0 0% 3 0 View 3D
USE1 Predictomes -0.438 3.84e-08 -0.352 0.324 0 0% 5 0 View 3D
CHN1 Predictomes 0.814 4.27e-04 0.212 0.606 0 0% 6 0 View 3D
RASGRF1 Predictomes -0.312 6.02e-33 -0.470 0.265 0 0% 21 0 View 3D
UTP6 Predictomes -0.366 1.43e-07 -0.274 0.363 0 0% 8 0 View 3D
RASGEF1A Predictomes -0.485 6.28e-16 -0.395 0.303 0 0% 9 0 View 3D
RALGAPA2 Predictomes 0.411 1.78e-02 -0.113 0.443 0 0% 11 0 View 3D
RASGEF1C Predictomes -0.343 2.20e-28 -0.442 0.279 0 0% 16 0 View 3D
RASGRP4 Predictomes 0.227 8.46e-16 -0.289 0.356 0 0% 23 0 View 3D
TRIO Predictomes -0.064 5.42e-12 -0.341 0.329 0 0% 9 0 View 3D
BRAF Predictomes -0.759 8.40e-26 -0.461 0.269 0 0% 12 0 View 3D
WBP4 Predictomes -0.715 2.73e-21 -0.487 0.257 0 0% 8 0 View 3D
CHN1 Predictomes -0.122 5.12e-04 -0.196 0.402 0 0% 7 0 View 3D
C2orf72 Predictomes 0.012 8.39e-06 -0.223 0.388 0 0% 9 0 View 3D
MAD2L1 Predictomes -0.386 1.99e-04 -0.184 0.408 4 44% 9 0 View 3D
RALGDS Predictomes -0.070 2.62e-28 -0.396 0.302 0 0% 25 0 View 3D
RALGDS Predictomes 0.268 1.54e-12 -0.258 0.371 0 0% 22 0 View 3D
TBC1D10B Predictomes 0.163 1.08e-13 -0.308 0.346 0 0% 14 0 View 3D
ADGRG1 Predictomes -0.367 2.09e-11 -0.348 0.326 0 0% 8 0 View 3D
RASGEF1A Predictomes -0.786 8.29e-38 -0.531 0.234 0 0% 14 0 View 3D
RASGRF2 Predictomes 0.110 3.23e-15 -0.306 0.347 0 0% 24 0 View 3D
RGL1 Predictomes 0.373 7.03e-07 -0.193 0.403 0 0% 18 0 View 3D
RGL1 Predictomes 0.213 1.92e-12 -0.262 0.369 0 0% 22 0 View 3D
SOS1 Predictomes -0.359 8.77e-37 -0.465 0.267 0 0% 20 0 View 3D
ARHGAP21 Predictomes 0.981 8.62e-07 0.237 0.618 0 0% 10 0 View 3D
RASAL2 Predictomes 0.339 2.49e-04 -0.195 0.402 0 0% 8 0 View 3D
USP6NL Predictomes 0.564 3.50e-02 -0.103 0.448 — — 10 0 View 3D
RAPH1 Predictomes -0.974 1.52e-26 -0.579 0.210 0 0% 7 0 View 3D
RAP1A Predictomes -0.820 5.22e-30 -0.481 0.260 0 0% 13 0 View 3D
ITSN1 Predictomes -0.415 2.01e-25 -0.515 0.242 0 0% 9 0 View 3D
RASGRP3 Predictomes 0.382 2.35e-07 -0.195 0.403 0 0% 20 0 View 3D
SIPA1L2 Predictomes 0.533 3.77e-05 -0.175 0.413 0 0% 14 0 View 3D
PTPN1 Predictomes -0.227 5.68e-22 -0.434 0.283 0 0% 11 0 View 3D
EEF1AKMT1 Predictomes -1.189 1.12e-35 -0.640 0.180 0 0% 8 0 View 3D
SIPA1L1 Predictomes 0.502 2.79e-06 -0.198 0.401 0 0% 14 0 View 3D
ARHGAP31 Predictomes -0.285 1.32e-09 -0.303 0.349 0 0% 9 0 View 3D
EXOSC5 Predictomes -0.470 5.55e-20 -0.426 0.287 0 0% 10 0 View 3D
MAPKAP1 Predictomes -0.695 1.32e-30 -0.507 0.247 0 0% 12 0 View 3D
PIK3R4 Predictomes -0.756 9.59e-45 -0.593 0.204 0 0% 13 0 View 3D
EIF2S2 Predictomes -1.107 1.76e-33 -0.653 0.174 0 0% 7 0 View 3D
RALGAPA1 Predictomes 0.684 3.85e-01 -0.052 0.474 — — 7 0 View 3D
SNAP47 Predictomes -1.638 8.48e-40 -0.771 0.114 0 0% 6 0 View 3D
RALGAPA1 Predictomes 0.612 1.41e-01 -0.086 0.457 — — 7 0 View 3D
PTPN1 Predictomes -0.624 1.87e-23 -0.513 0.244 0 0% 8 0 View 3D
RASGEF1C Predictomes -0.464 1.15e-44 -0.543 0.228 0 0% 18 0 View 3D
TIAM1 Predictomes -0.293 3.44e-19 -0.410 0.295 1 9% 11 0 View 3D
EXOSC5 Predictomes -0.743 1.65e-28 -0.515 0.242 0 0% 10 0 View 3D
RASA1 Predictomes 0.265 2.33e-07 -0.215 0.392 0 0% 15 0 View 3D
NPM1 Predictomes -0.872 1.47e-28 -0.502 0.249 0 0% 11 0 View 3D
FGD6 Predictomes -0.340 2.15e-22 -0.500 0.250 0 0% 8 0 View 3D
RAPGEF2 Predictomes -0.498 8.40e-47 -0.506 0.247 0 0% 25 0 View 3D
RASAL2 Predictomes -0.955 3.35e-48 -0.694 0.153 0 0% 10 0 View 3D
ATP5F1A Predictomes -0.582 3.85e-17 -0.460 0.270 0 0% 7 0 View 3D
RALGAPA1 Predictomes 0.640 2.40e-01 -0.065 0.467 — — 8 0 View 3D
NRXN3 Predictomes -1.428 9.94e-37 -0.688 0.156 0 0% 7 0 View 3D
IQGAP1 Predictomes 0.547 2.58e-04 -0.176 0.412 0 0% 10 0 View 3D
PLXNC1 Predictomes 0.355 6.98e-02 -0.075 0.462 0 0% 25 0 View 3D
CYFIP1 Predictomes -1.091 9.88e-38 -0.606 0.197 0 0% 10 0 View 3D
SIPA1L2 Predictomes 0.503 2.97e-06 -0.198 0.401 0 0% 14 0 View 3D
RAP1A Predictomes -0.826 2.77e-23 -0.450 0.275 0 0% 11 0 View 3D
DAB2IP Predictomes 0.677 1.86e-01 -0.070 0.465 0 0% 9 0 View 3D
TBC1D10B Predictomes 0.093 4.01e-18 -0.349 0.325 0 0% 15 0 View 3D
TBC1D10A Predictomes 0.166 3.31e-14 -0.313 0.343 0 0% 14 0 View 3D
RALGAPA2 Predictomes 0.481 9.35e-04 -0.168 0.416 0 0% 9 0 View 3D
ADGRG1 Predictomes -0.098 7.23e-06 -0.249 0.376 0 0% 7 0 View 3D
FRMPD1 Predictomes -0.958 3.56e-36 -0.651 0.174 0 0% 8 0 View 3D
OSBPL10 Predictomes -0.834 3.81e-18 -0.510 0.245 2 33% 6 0 View 3D
RAPGEF6 Predictomes -0.440 5.22e-38 -0.497 0.252 0 0% 19 0 View 3D
NRXN3 Predictomes -0.936 4.53e-24 -0.520 0.240 0 0% 8 0 View 3D
BRAF Predictomes -0.756 6.09e-24 -0.444 0.278 0 0% 12 0 View 3D
ZDHHC5 Predictomes -0.468 5.29e-12 -0.403 0.298 0 0% 6 0 View 3D
ARHGAP21 Predictomes 0.669 8.80e-02 0.081 0.541 0 0% 12 0 View 3D
NRXN3 Predictomes -1.440 3.43e-31 -0.675 0.163 0 0% 6 0 View 3D
C2orf72 Predictomes -0.800 1.97e-18 -0.555 0.222 0 0% 5 0 View 3D
RALGPS2 Predictomes 0.121 6.78e-15 -0.308 0.346 0 0% 17 0 View 3D
RASGRP1 Predictomes 0.273 4.64e-11 -0.236 0.382 0 0% 24 0 View 3D
RPS10 Predictomes -0.610 1.13e-16 -0.408 0.296 0 0% 9 0 View 3D
RAP1A Predictomes -0.810 6.09e-20 -0.448 0.276 0 0% 9 0 View 3D
NPM1 Predictomes -0.809 1.75e-18 -0.430 0.285 0 0% 9 0 View 3D
RAP2C Predictomes -0.901 3.33e-28 -0.484 0.258 0 0% 12 0 View 3D
PLXNA2 Predictomes 0.555 3.13e-03 -0.124 0.438 0 0% 16 0 View 3D
TRIO Predictomes -0.283 8.41e-22 -0.422 0.289 0 0% 12 0 View 3D
FGD1 Predictomes -0.233 7.01e-19 -0.385 0.307 0 0% 12 0 View 3D
PLXNC1 Predictomes 0.488 5.26e-05 -0.162 0.419 0 0% 17 0 View 3D
UTP6 Predictomes -0.198 1.29e-07 -0.239 0.380 0 0% 11 0 View 3D
RAPGEF2 Predictomes -0.439 3.45e-39 -0.481 0.259 0 0% 21 0 View 3D
SGSM2 Predictomes -0.070 1.95e-19 -0.379 0.310 — — 14 0 View 3D
RAPH1 Predictomes -0.966 4.37e-27 -0.587 0.207 0 0% 7 0 View 3D
ARAF Predictomes -0.724 5.46e-28 -0.430 0.285 0 0% 16 0 View 3D
RPS10 Predictomes -0.573 1.73e-18 -0.429 0.286 0 0% 9 0 View 3D
EIF2S2 Predictomes -1.152 7.12e-33 -0.691 0.155 0 0% 6 0 View 3D
SOS1 Predictomes -0.606 9.94e-37 -0.538 0.231 0 0% 16 0 View 3D
RGL1 Predictomes 0.189 7.31e-15 -0.292 0.354 0 0% 21 0 View 3D
SGSM2 Predictomes -0.059 2.64e-16 -0.351 0.325 — — 13 0 View 3D
EXOC1 Predictomes -0.701 4.09e-29 -0.574 0.213 0 0% 8 0 View 3D
USP6NL Predictomes 0.502 2.33e-02 -0.107 0.447 — — 11 0 View 3D
FGD6 Predictomes -0.156 4.28e-15 -0.428 0.286 0 0% 7 0 View 3D
NRAS Predictomes -0.979 4.04e-27 -0.527 0.237 0 0% 9 0 View 3D
RIN1 Predictomes -1.155 2.76e-49 -0.668 0.166 0 0% 11 0 View 3D
USO1 Predictomes -1.165 2.82e-38 -0.662 0.169 0 0% 8 0 View 3D
RAPGEF6 Predictomes -0.456 1.11e-42 -0.521 0.239 0 0% 19 0 View 3D
RASGRP3 Predictomes 0.336 1.40e-09 -0.224 0.388 0 0% 21 0 View 3D
ARHGDIA Predictomes -0.311 3.85e-11 -0.312 0.344 0 0% 10 0 View 3D
ARHGAP32 Predictomes -0.055 3.84e-04 -0.200 0.400 0 0% 7 0 View 3D
PIK3CA Predictomes -0.994 9.78e-28 -0.633 0.183 0 0% 6 0 View 3D
ARAF Predictomes -0.693 6.66e-25 -0.429 0.285 0 0% 14 0 View 3D
FAM91A1 Predictomes 1.055 9.02e-01 0.009 0.504 1 11% 5 0 View 3D
SIPA1L1 Predictomes -0.746 8.32e-09 -0.413 0.294 0 0% 4 0 View 3D
NRAS Predictomes -0.952 2.02e-27 -0.508 0.246 0 0% 10 0 View 3D
C2orf72 Predictomes -0.562 5.68e-08 -0.438 0.281 0 0% 3 0 View 3D
ITSN1 Predictomes -0.584 1.59e-38 -0.589 0.205 0 0% 11 0 View 3D
YKT6 Predictomes -0.473 7.26e-18 -0.439 0.280 0 0% 8 0 View 3D
ZDHHC5 Predictomes -0.493 1.24e-12 -0.448 0.276 0 0% 5 0 View 3D
YKT6 Predictomes -0.259 2.44e-11 -0.342 0.329 0 0% 8 0 View 3D
RGL3 Predictomes 0.085 1.75e-20 -0.334 0.333 0 0% 26 0 View 3D
MAD2L1 Predictomes -0.139 5.03e-02 0.110 0.555 4 44% 7 0 View 3D
TIAM1 Predictomes -0.588 3.36e-43 -0.601 0.199 1 9% 12 0 View 3D
TBC1D10A Predictomes 0.387 2.19e-06 -0.217 0.392 0 0% 11 0 View 3D
RPS10 Predictomes -0.402 5.34e-13 -0.354 0.323 0 0% 9 0 View 3D
ARHGAP32 Predictomes -0.416 7.81e-15 -0.404 0.298 0 0% 8 0 View 3D
OSBPL10 Predictomes -0.563 2.66e-13 -0.515 0.242 2 33% 4 0 View 3D
RRAS2 Predictomes -0.036 8.78e-03 0.138 0.569 1 10% 8 0 View 3D
NME6 Predictomes -1.045 3.65e-31 -0.600 0.200 0 0% 8 0 View 3D
ATP5F1A Predictomes -0.566 1.15e-29 -0.493 0.254 0 0% 12 0 View 3D
FAM91A1 Predictomes 1.001 8.72e-01 -0.010 0.495 1 11% 7 0 View 3D
NRAS Predictomes -0.979 5.16e-40 -0.558 0.221 0 0% 13 0 View 3D
IQGAP1 Predictomes 0.669 5.98e-02 -0.098 0.451 0 0% 9 0 View 3D
MCF2L Predictomes -0.300 2.35e-19 -0.377 0.312 2 14% 14 0 View 3D
RASGRP3 Predictomes 0.277 1.46e-12 -0.258 0.371 0 0% 22 0 View 3D
CYFIP1 Predictomes -1.401 1.68e-38 -0.718 0.141 0 0% 7 0 View 3D
PLXNB2 Predictomes 0.340 2.04e-07 -0.206 0.397 0 0% 18 0 View 3D
PLXNB2 Predictomes 0.574 7.51e-03 -0.113 0.443 0 0% 15 0 View 3D
CHN1 Predictomes 0.753 4.64e-05 0.265 0.632 0 0% 5 0 View 3D
CHERP Predictomes 0.728 7.00e-01 0.028 0.514 0 0% 5 0 View 3D
EEF1AKMT1 Predictomes -1.329 8.53e-34 -0.660 0.170 0 0% 7 0 View 3D
FRMPD1 Predictomes -1.169 4.63e-40 -0.678 0.161 0 0% 8 0 View 3D
RAF1 Predictomes -0.698 4.80e-26 -0.425 0.287 0 0% 15 0 View 3D
NF1 Predictomes 0.377 7.48e-06 -0.188 0.406 1 7% 14 0 View 3D
DAB2IP Predictomes -0.820 9.53e-42 -0.623 0.188 0 0% 11 0 View 3D
PIK3R4 Predictomes -0.719 8.71e-38 -0.579 0.210 0 0% 11 0 View 3D
RGL2 Predictomes 0.088 1.86e-20 -0.331 0.335 0 0% 27 0 View 3D
PTPN1 Predictomes -1.206 1.15e-40 -0.690 0.155 0 0% 8 0 View 3D
RALGPS2 Predictomes 0.114 2.89e-15 -0.311 0.345 0 0% 17 0 View 3D
TTC4 Predictomes -0.344 2.17e-07 -0.304 0.348 0 0% 6 0 View 3D
HRAS Predictomes -0.913 3.87e-27 -0.505 0.247 0 0% 10 0 View 3D
RRAS2 Predictomes -1.208 6.34e-23 -0.624 0.188 1 10% 5 0 View 3D
TBC1D5 Predictomes -0.141 7.38e-18 -0.389 0.305 0 0% 11 0 View 3D
RAPGEF2 Predictomes -0.541 1.03e-50 -0.540 0.230 0 0% 24 0 View 3D
CHERP Predictomes -0.494 3.59e-05 -0.298 0.351 0 0% 4 0 View 3D
SNAP47 Predictomes -1.659 6.57e-42 -0.794 0.103 0 0% 6 0 View 3D
WBP4 Predictomes -0.737 7.00e-22 -0.493 0.253 0 0% 8 0 View 3D
RALGDS Predictomes 0.173 1.45e-11 -0.248 0.376 0 0% 24 0 View 3D
PIK3CB Predictomes -1.234 1.38e-38 -0.702 0.149 0 0% 7 0 View 3D
LRP8 Predictomes -0.317 1.35e-05 -0.308 0.346 0 0% 4 0 View 3D
MAD2L1 Predictomes -0.246 6.19e-01 0.028 0.514 4 44% 8 0 View 3D
ATP5F1B Predictomes -0.497 3.58e-13 -0.424 0.288 0 0% 6 0 View 3D
SNAP47 Predictomes -1.687 2.29e-42 -0.798 0.101 0 0% 6 0 View 3D
RGL2 Predictomes 0.109 6.48e-18 -0.302 0.349 0 0% 26 0 View 3D
IL1RAP Predictomes -1.324 1.98e-54 -0.758 0.121 0 0% 9 0 View 3D
RASGEF1C Predictomes -0.147 5.79e-23 -0.375 0.312 0 0% 18 0 View 3D
MCF2L Predictomes -0.521 1.88e-37 -0.580 0.210 2 14% 11 0 View 3D
RASGRP1 Predictomes 0.277 3.55e-13 -0.266 0.367 0 0% 22 0 View 3D
TTC4 Predictomes -0.226 2.78e-04 -0.233 0.383 0 0% 5 0 View 3D
NF1 Predictomes 0.756 1.12e-02 0.121 0.560 1 7% 11 0 View 3D
ARHGAP39 Predictomes 0.406 6.52e-02 -0.101 0.450 0 0% 8 0 View 3D
RASA1 Predictomes 0.232 1.47e-09 -0.250 0.375 0 0% 15 0 View 3D
TBC1D5 Predictomes 0.225 8.75e-06 -0.247 0.377 0 0% 7 0 View 3D
EEF1AKMT1 Predictomes -1.347 1.06e-33 -0.659 0.170 0 0% 7 0 View 3D
HRAS Predictomes -0.989 1.84e-37 -0.556 0.222 0 0% 12 0 View 3D
USO1 Predictomes -1.006 1.28e-38 -0.605 0.197 0 0% 10 0 View 3D
RGL3 Predictomes 0.092 8.10e-22 -0.347 0.326 0 0% 23 0 View 3D
RGL2 Predictomes 0.119 3.53e-17 -0.313 0.344 0 0% 23 0 View 3D
USO1 Predictomes -1.031 1.43e-40 -0.622 0.189 0 0% 10 0 View 3D
TBC1D5 Predictomes -0.169 2.80e-18 -0.394 0.303 0 0% 11 0 View 3D
RBM12 Predictomes -0.196 8.47e-08 -0.234 0.383 3 21% 14 0 View 3D
IQGAP1 Predictomes 0.298 1.25e-05 -0.231 0.385 0 0% 8 0 View 3D
PIK3CB Predictomes -0.982 2.05e-31 -0.570 0.215 0 0% 9 0 View 3D
AFDN Predictomes -0.531 1.89e-28 -0.437 0.281 2 12% 16 0 View 3D
ZDHHC5 Predictomes -0.322 2.85e-07 -0.328 0.336 0 0% 5 0 View 3D
ATP5F1A Predictomes -0.604 1.97e-32 -0.518 0.241 0 0% 12 0 View 3D
ARHGAP31 Predictomes -0.151 2.67e-05 -0.222 0.389 0 0% 8 0 View 3D
RAF1 Predictomes -0.700 4.78e-26 -0.437 0.281 0 0% 14 0 View 3D
EXOC1 Predictomes -0.754 2.97e-29 -0.576 0.212 0 0% 8 0 View 3D
RASA1 Predictomes 0.296 8.71e-07 -0.211 0.395 0 0% 14 0 View 3D
RALGPS2 Predictomes -0.124 1.12e-31 -0.421 0.289 0 0% 22 0 View 3D
RAPH1 Predictomes -0.957 9.47e-27 -0.582 0.209 0 0% 7 0 View 3D
RIN1 Predictomes -1.163 1.37e-34 -0.714 0.143 0 0% 6 0 View 3D
ARHGAP32 Predictomes -0.050 1.72e-10 -0.317 0.341 0 0% 9 0 View 3D
NME6 Predictomes -0.256 1.69e-17 -0.402 0.299 0 0% 10 0 View 3D
IL1RAP Predictomes -1.322 2.87e-54 -0.757 0.121 0 0% 9 0 View 3D
ITSN1 Predictomes -0.409 9.35e-26 -0.517 0.242 0 0% 9 0 View 3D
FGD1 Predictomes -0.283 1.91e-20 -0.436 0.282 0 0% 10 0 View 3D
RAF1 Predictomes -0.738 1.13e-28 -0.439 0.281 0 0% 16 0 View 3D
TBC1D10B Predictomes 0.122 1.77e-17 -0.343 0.328 0 0% 15 0 View 3D
RGL3 Predictomes 0.200 1.58e-14 -0.290 0.355 0 0% 20 0 View 3D
ARHGAP39 Predictomes 0.619 6.71e-02 0.101 0.550 0 0% 8 0 View 3D
RASGRF2 Predictomes -0.377 3.35e-33 -0.479 0.261 0 0% 20 0 View 3D
SIPA1L2 Predictomes 0.280 7.63e-19 -0.350 0.325 0 0% 16 0 View 3D
RIN1 Predictomes -1.141 4.88e-33 -0.695 0.153 0 0% 6 0 View 3D
RASGEF1A Predictomes -0.346 4.47e-29 -0.443 0.279 0 0% 16 0 View 3D
EXOSC5 Predictomes -0.721 4.42e-28 -0.511 0.244 0 0% 10 0 View 3D
ATP5F1B Predictomes -0.493 1.78e-13 -0.430 0.285 0 0% 6 0 View 3D
ARAF Predictomes -0.647 1.11e-22 -0.397 0.302 0 0% 15 0 View 3D
ARHGAP31 Predictomes 0.115 1.66e-04 -0.182 0.409 0 0% 10 0 View 3D
ARHGDIA Predictomes -0.348 3.86e-14 -0.373 0.314 0 0% 9 0 View 3D
AFDN Predictomes -1.089 4.17e-42 -0.617 0.192 2 12% 11 0 View 3D
RBM12 Predictomes -0.255 1.44e-14 -0.320 0.340 3 21% 14 0 View 3D
TBC1D10A Predictomes -0.315 2.10e-28 -0.456 0.272 0 0% 14 0 View 3D
USE1 Predictomes -0.472 5.45e-09 -0.372 0.314 0 0% 5 0 View 3D
PLXNC1 Predictomes 0.267 1.91e-12 -0.269 0.365 0 0% 20 0 View 3D
ARHGAP39 Predictomes -0.799 3.70e-13 -0.520 0.240 0 0% 4 0 View 3D
TAOK3 Predictomes -0.575 5.91e-11 -0.385 0.308 0 0% 6 0 View 3D
RASGRF1 Predictomes 0.000 2.71e-20 -0.353 0.323 0 0% 25 0 View 3D
AFDN Predictomes -1.176 1.24e-47 -0.679 0.161 2 12% 10 0 View 3D
PIK3CB Predictomes -1.236 1.10e-38 -0.703 0.148 0 0% 7 0 View 3D
RASAL2 Predictomes -0.037 4.01e-19 -0.407 0.297 0 0% 11 0 View 3D
HRAS Predictomes -0.789 1.06e-23 -0.438 0.281 0 0% 12 0 View 3D
EIF2S2 Predictomes -1.116 1.22e-31 -0.677 0.162 0 0% 6 0 View 3D
MAPKAP1 Predictomes -0.639 7.02e-28 -0.510 0.245 0 0% 10 0 View 3D
RASGRP4 Predictomes 0.319 1.39e-10 -0.238 0.381 0 0% 21 0 View 3D
CYFIP1 Predictomes -1.138 9.15e-40 -0.651 0.175 0 0% 9 0 View 3D
MCF2L Predictomes -0.421 8.40e-25 -0.507 0.246 2 14% 9 0 View 3D
SOS1 Predictomes -0.324 3.23e-33 -0.451 0.275 0 0% 19 0 View 3D
FGD1 Predictomes -0.228 7.31e-19 -0.414 0.293 0 0% 10 0 View 3D
USP6NL Predictomes 0.565 3.15e-02 -0.105 0.447 — — 10 0 View 3D
RAPGEF6 Predictomes -0.302 2.60e-24 -0.425 0.288 0 0% 15 0 View 3D
FRMPD1 Predictomes -0.975 1.39e-32 -0.648 0.176 0 0% 7 0 View 3D
FGD6 Predictomes -0.350 4.33e-22 -0.499 0.251 0 0% 8 0 View 3D
KIF11 Predictomes -0.865 1.87e-24 -0.556 0.222 0 0% 7 0 View 3D
MAPKAP1 Predictomes -0.570 3.01e-21 -0.417 0.292 0 0% 12 0 View 3D
PLXNA1 Predictomes 0.452 2.81e-08 -0.229 0.386 0 0% 15 0 View 3D
PLXNA2 Predictomes 0.442 1.04e-04 -0.168 0.416 0 0% 14 0 View 3D
CHERP Predictomes -0.728 1.01e-06 -0.403 0.298 0 0% 3 0 View 3D
WBP4 Predictomes -0.809 3.20e-22 -0.497 0.251 0 0% 8 0 View 3D
PIK3CA Predictomes -0.812 3.56e-24 -0.474 0.263 0 0% 10 0 View 3D
DAB2IP Predictomes -0.956 1.13e-47 -0.692 0.154 0 0% 10 0 View 3D
PTPN14 Zhang_et_al -0.844 5.64e-25 -0.472 0.264 0 0% 11 0 View 3D
SLC4A2 Zhang_et_al -1.154 1.00e-15 -0.662 0.169 0 0% 3 0 View 3D
YWHAE Zhang_et_al -1.070 1.24e-21 -0.617 0.192 0 0% 5 0 View 3D
DCUN1D3 Zhang_et_al -1.792 1.38e-38 -0.834 0.083 0 0% 5 0 View 3D
KRAS RCSB_PDB 0.285 8.03e-14 0.405 0.702 4 57% 7 0 View 3D
KRAS RCSB_PDB 0.151 1.16e-06 0.285 0.643 4 57% 6 0 View 3D
KRAS RCSB_PDB -1.113 1.04e-30 -0.668 0.166 4 57% 6 0 View 3D
KRAS RCSB_PDB -1.032 4.21e-30 -0.661 0.169 4 57% 6 0 View 3D
KRAS RCSB_PDB 0.290 1.12e-13 0.403 0.702 4 57% 7 0 View 3D
KRAS RCSB_PDB 0.076 5.14e-05 0.223 0.612 4 57% 7 0 View 3D
MAPKAP1 RCSB_PDB -0.411 1.27e-01 -0.114 0.443 0 0% 4 0 View 3D
MAPKAP1 RCSB_PDB -0.962 2.21e-23 -0.628 0.186 0 0% 5 0 View 3D
MAPKAP1 RCSB_PDB -0.712 2.39e-39 -0.527 0.236 0 0% 15 0 View 3D
SOS1 RCSB_PDB 0.109 1.79e-09 -0.224 0.388 1 5% 20 0 View 3D
BRAF RCSB_PDB -1.052 5.39e-34 -0.626 0.187 0 0% 8 0 View 3D
RGL2 RCSB_PDB -0.987 2.03e-34 -0.572 0.214 0 0% 10 0 View 3D
SOS1 RCSB_PDB 0.198 9.55e-11 -0.234 0.383 1 5% 22 0 View 3D
RAF1 RCSB_PDB -0.523 7.44e-19 -0.350 0.325 0 0% 16 0 View 3D
PLAAT3 RCSB_PDB 1.134 1.44e-08 0.281 0.640 1 11% 9 0 View 3D
PPIA RCSB_PDB -0.499 2.35e-08 -0.396 0.302 0 0% 4 0 View 3D
LZTR1 RCSB_PDB -0.291 1.63e-23 -0.419 0.291 0 0% 13 0 View 3D
PPP1CA RCSB_PDB -0.447 1.28e-03 -0.231 0.385 — — 4 0 View 3D
SOS1 RCSB_PDB 0.201 3.12e-10 -0.228 0.386 1 5% 22 0 View 3D
PPIA RCSB_PDB -0.546 1.74e-09 -0.489 0.255 0 0% 3 0 View 3D
SOS1 RCSB_PDB 0.193 2.44e-11 -0.246 0.377 1 5% 21 0 View 3D
KRAS RCSB_PDB -0.857 1.43e-07 -0.372 0.314 4 57% 4 0 View 3D
KRAS RCSB_PDB -0.829 1.70e-07 -0.370 0.315 4 57% 4 0 View 3D
RAF1 RCSB_PDB -1.105 7.86e-31 -0.669 0.165 0 0% 6 0 View 3D
SOS1 RCSB_PDB -0.038 1.02e-18 -0.316 0.342 1 5% 22 0 View 3D
PPIA RCSB_PDB -0.499 3.68e-08 -0.390 0.305 0 0% 4 0 View 3D
RAF1 RCSB_PDB -0.960 3.31e-33 -0.618 0.191 0 0% 8 0 View 3D
PPIA RCSB_PDB -0.508 7.33e-10 -0.501 0.250 0 0% 3 0 View 3D
RAF1 RCSB_PDB -1.043 1.82e-32 -0.644 0.178 0 0% 7 0 View 3D
RAF1 RCSB_PDB -0.624 2.31e-24 -0.397 0.301 0 0% 16 0 View 3D
BRAF RCSB_PDB -1.045 3.71e-31 -0.676 0.162 0 0% 6 0 View 3D