MRAS — Activity

🧬 View Structure

28 interactions

DMS Score Heatmap Scroll horizontally • click a column to see interactions • ■ purple strip = interface positions

M_R_Ras_like A V I L G F Y W C M P S T N Q D E H K R * 20 40 60 80 100 120 140 160 180 200 0.45 1.00 1.50
Click a position to see interactions — ■ orange strip marks interface positions (darker = more interactions)

Significant Interactions

Interactor Predictor Log FC p-value (FDR) Cliff's Delta AUROC Unique Pos. % Unique # Interface Clashes Structure
RAF1 Predictomes -0.239 2.85e-10 -0.325 0.337 0 0% 8 0 View 3D
RAPGEF6 Predictomes -0.160 2.15e-08 -0.242 0.379 0 0% 13 0 View 3D
BRAF Predictomes -0.156 3.09e-05 -0.217 0.391 0 0% 8 0 View 3D
RALGDS Predictomes -0.286 1.45e-35 -0.469 0.265 5 24% 21 0 View 3D
RALGDS Predictomes -0.301 3.22e-46 -0.508 0.246 5 24% 25 0 View 3D
BRAF Predictomes -0.277 1.85e-19 -0.445 0.277 0 0% 9 0 View 3D
RAPGEF2 Predictomes -0.302 5.18e-45 -0.490 0.255 0 0% 25 0 View 3D
RAPGEF5 Predictomes -0.324 1.06e-38 -0.529 0.235 0 0% 15 0 View 3D
RAPGEF2 Predictomes -0.335 2.11e-49 -0.545 0.227 0 0% 21 0 View 3D
RALGDS Predictomes -0.282 1.96e-33 -0.477 0.261 5 24% 19 0 View 3D
RAPGEF5 Predictomes -0.263 1.58e-26 -0.435 0.282 0 0% 15 0 View 3D
RAPGEF5 Predictomes -0.175 1.06e-16 -0.311 0.344 0 0% 19 0 View 3D
BRAF Predictomes -0.414 1.62e-40 -0.623 0.188 0 0% 10 0 View 3D
RAPGEF2 Predictomes -0.229 4.69e-22 -0.386 0.307 0 0% 16 0 View 3D
RAPGEF6 Predictomes -0.300 2.61e-42 -0.503 0.249 0 0% 21 0 View 3D
RAPGEF6 Predictomes -0.169 6.45e-11 -0.279 0.360 0 0% 14 0 View 3D
RAF1 Predictomes -0.316 8.99e-31 -0.491 0.255 0 0% 13 0 View 3D
RAF1 Predictomes -0.377 3.47e-32 -0.555 0.223 0 0% 10 0 View 3D
SHOC2 RCSB_PDB -0.175 5.48e-04 -0.284 0.358 0 0% 3 0 View 3D
SHOC2 RCSB_PDB -0.172 5.64e-04 -0.283 0.358 0 0% 3 0 View 3D
PIK3CA RCSB_PDB -0.445 1.16e-46 -0.664 0.168 0 0% 10 0 View 3D
MRAS RCSB_PDB -0.354 9.86e-43 -0.542 0.229 1 7% 15 0 View 3D
MRAS RCSB_PDB -0.259 2.49e-33 -0.445 0.278 1 7% 19 0 View 3D
PPP1CA RCSB_PDB -0.142 8.48e-08 -0.252 0.374 1 10% 10 0 View 3D
LZTR1 RCSB_PDB -0.175 5.93e-15 -0.311 0.345 3 20% 15 0 View 3D
PPP1CC RCSB_PDB -0.109 1.42e-04 -0.188 0.406 1 11% 9 0 View 3D
PPP1CA RCSB_PDB -0.136 1.91e-07 -0.246 0.377 1 10% 10 0 View 3D
PPP1CA RCSB_PDB -0.083 9.48e-04 -0.165 0.418 1 10% 9 0 View 3D