SOS2 — Abundance_hsp90i

🧬 View Structure

17 interactions

DMS Score Heatmap Scroll horizontally • click a column to see interactions • ■ purple strip = interface positions

PH_SOS RasGEFN RasGEF A V I L G F Y W C M P S T N Q D E H K R * 540 560 580 600 620 640 660 680 700 720 740 760 780 800 820 840 860 880 900 920 940 960 980 1000 1020 0.25 1.00 1.54
Click a position to see interactions — ■ orange strip marks interface positions (darker = more interactions)

Significant Interactions

Interactor Predictor Log FC p-value (FDR) Cliff's Delta AUROC Unique Pos. % Unique # Interface Clashes Structure
RAP1B Predictomes 0.274 4.32e-42 0.507 0.754 3 17% 18 0 View 3D
RAP1B Predictomes 0.270 2.61e-43 0.494 0.747 3 17% 20 0 View 3D
RAP1B Predictomes 0.263 9.66e-42 0.473 0.736 3 17% 21 0 View 3D
SOS1 Zhang_et_al -0.063 1.80e-01 -0.110 0.445 — — 4 0 View 3D
SHC1 Zhang_et_al 0.176 3.91e-06 0.277 0.639 4 57% 7 0 View 3D
ZNF410 Zhang_et_al 0.271 2.31e-21 0.480 0.740 2 20% 10 0 View 3D
RASL11B Zhang_et_al 0.208 1.27e-12 0.353 0.676 1 10% 10 0 View 3D
ARHGAP39 Zhang_et_al 0.112 2.19e-02 0.174 0.587 — — 5 0 View 3D
RASL11A Zhang_et_al 0.231 1.49e-17 0.403 0.702 1 9% 11 0 View 3D
CD2AP Zhang_et_al 0.164 1.44e-07 0.290 0.645 2 25% 8 0 View 3D
ABI1 Zhang_et_al 0.164 8.38e-04 0.294 0.647 0 0% 3 0 View 3D
FOXO1 Zhang_et_al 0.230 2.62e-17 0.385 0.693 1 8% 12 0 View 3D
NCK2 Zhang_et_al 0.270 5.36e-22 0.443 0.722 1 9% 11 0 View 3D
EGFR Zhang_et_al 0.268 5.19e-18 0.497 0.749 2 29% 7 0 View 3D
RERG Zhang_et_al 0.177 3.06e-06 0.308 0.654 0 0% 6 0 View 3D
BIN1 Zhang_et_al 0.340 2.07e-14 0.584 0.792 0 0% 4 0 View 3D
STARD13 Zhang_et_al 0.148 3.96e-03 0.206 0.603 — — 5 0 View 3D