SOS2 — Activity

🧬 View Structure

17 interactions

DMS Score Heatmap Scroll horizontally • click a column to see interactions • ■ purple strip = interface positions

PH_SOS RasGEFN RasGEF A V I L G F Y W C M P S T N Q D E H K R * 540 560 580 600 620 640 660 680 700 720 740 760 780 800 820 840 860 880 900 920 940 960 980 1000 1020 0.29 1.00 2.32
Click a position to see interactions — ■ orange strip marks interface positions (darker = more interactions)

Significant Interactions

Interactor Predictor Log FC p-value (FDR) Cliff's Delta AUROC Unique Pos. % Unique # Interface Clashes Structure
RAP1B Predictomes -0.793 6.65e-108 -0.746 0.127 3 17% 18 0 View 3D
RAP1B Predictomes -0.809 2.74e-122 -0.762 0.119 3 17% 20 0 View 3D
RAP1B Predictomes -0.752 2.68e-111 -0.712 0.144 3 17% 21 0 View 3D
SOS1 Zhang_et_al 0.002 1.67e-01 0.107 0.553 — — 4 0 View 3D
SHC1 Zhang_et_al -0.431 3.62e-17 -0.443 0.279 3 43% 7 0 View 3D
ZNF410 Zhang_et_al -0.875 6.64e-65 -0.753 0.124 2 20% 10 0 View 3D
RASL11B Zhang_et_al -0.618 3.89e-37 -0.563 0.219 1 10% 10 0 View 3D
ARHGAP39 Zhang_et_al -0.129 1.77e-01 -0.094 0.453 — — 5 0 View 3D
RASL11A Zhang_et_al -0.709 6.10e-51 -0.634 0.183 1 9% 11 0 View 3D
CD2AP Zhang_et_al -0.492 4.67e-21 -0.464 0.268 2 25% 8 0 View 3D
ABI1 Zhang_et_al -0.435 4.77e-11 -0.524 0.238 0 0% 3 0 View 3D
FOXO1 Zhang_et_al -0.648 6.10e-51 -0.611 0.195 1 8% 12 0 View 3D
NCK2 Zhang_et_al -0.758 3.89e-60 -0.692 0.154 1 9% 11 0 View 3D
EGFR Zhang_et_al -0.494 5.48e-26 -0.555 0.223 2 29% 7 0 View 3D
RERG Zhang_et_al -0.654 7.01e-24 -0.569 0.215 0 0% 6 0 View 3D
BIN1 Zhang_et_al -1.216 9.64e-37 -0.866 0.067 0 0% 4 0 View 3D
STARD13 Zhang_et_al -0.393 1.03e-09 -0.381 0.310 0 0% 5 0 View 3D