ARAF — Abundance

🧬 View Structure

66 interactions

DMS Score Heatmap Scroll horizontally • click a column to see interactions • ■ purple strip = interface positions

RBD_ARAF C1_A_C-Raf STKc_A-Raf A V I L G F Y W C M P S T N Q D E H K R * 20 40 60 80 100 120 140 160 180 200 220 240 260 280 300 320 340 360 380 400 420 440 460 480 500 520 540 560 580 600 0.27 1.00 1.50
Click a position to see interactions — ■ orange strip marks interface positions (darker = more interactions)

Significant Interactions

Interactor Predictor Log FC p-value (FDR) Cliff's Delta AUROC Unique Pos. % Unique # Interface Clashes Structure
KSR1 Predictomes -0.001 6.51e-01 0.021 0.510 — — 13 0 View 3D
MAP2K1 Predictomes -0.056 1.41e-04 -0.158 0.421 — — 13 0 View 3D
YWHAH Predictomes 0.009 3.28e-01 -0.043 0.479 — — 13 0 View 3D
BRAF Predictomes -0.069 4.16e-05 -0.183 0.409 — — 11 0 View 3D
YWHAH Predictomes 0.021 8.50e-01 -0.009 0.495 — — 12 0 View 3D
RRAS2 Predictomes 0.063 2.84e-19 0.355 0.678 — — 14 0 View 3D
YWHAG Predictomes 0.014 5.13e-01 -0.029 0.485 — — 13 0 View 3D
YWHAH Predictomes 0.017 7.10e-01 -0.018 0.491 — — 12 0 View 3D
RAF1 Predictomes -0.029 2.34e-02 -0.092 0.454 — — 14 0 View 3D
RAF1 Predictomes -0.034 1.21e-02 -0.103 0.448 — — 14 0 View 3D
SFN Predictomes 0.075 4.73e-02 0.111 0.556 — — 7 0 View 3D
MAP2K3 Predictomes -0.070 1.91e-05 -0.217 0.391 — — 8 0 View 3D
MAP2K3 Predictomes -0.070 6.56e-06 -0.217 0.392 — — 9 0 View 3D
MAP2K2 Predictomes -0.060 1.04e-05 -0.176 0.412 — — 14 0 View 3D
MAP2K2 Predictomes -0.056 1.51e-04 -0.158 0.421 — — 13 0 View 3D
YWHAB Predictomes 0.026 6.51e-01 0.021 0.510 — — 13 0 View 3D
YWHAB Predictomes 0.029 4.77e-01 0.031 0.515 — — 14 0 View 3D
KSR1 Predictomes -0.014 5.49e-01 -0.027 0.487 — — 13 0 View 3D
MAP2K5 Predictomes -0.051 2.06e-05 -0.189 0.405 — — 11 0 View 3D
YWHAZ Predictomes 0.022 9.08e-01 -0.005 0.497 — — 12 0 View 3D
RRAS Predictomes 0.128 1.93e-21 0.481 0.740 8 100% 8 0 View 3D
NRAS Predictomes 0.065 2.38e-19 0.355 0.678 — — 14 0 View 3D
YWHAZ Predictomes 0.014 5.45e-01 -0.027 0.486 — — 13 0 View 3D
MAP2K5 Predictomes -0.078 1.62e-07 -0.251 0.375 — — 9 0 View 3D
NRAS Predictomes 0.070 1.38e-20 0.367 0.683 — — 14 0 View 3D
KRAS Predictomes 0.063 2.14e-19 0.353 0.676 — — 14 0 View 3D
MAP2K1 Predictomes -0.060 1.33e-05 -0.174 0.413 — — 14 0 View 3D
MAP2K2 Predictomes -0.048 6.50e-04 -0.134 0.433 — — 15 0 View 3D
MAP2K5 Predictomes -0.074 2.30e-09 -0.231 0.384 — — 15 0 View 3D
YWHAQ Predictomes 0.020 8.38e-01 -0.010 0.495 — — 12 0 View 3D
KRAS Predictomes 0.066 1.73e-19 0.356 0.678 — — 14 0 View 3D
STK11 Predictomes -0.054 1.94e-04 -0.159 0.421 — — 12 0 View 3D
BRAF Predictomes -0.070 5.12e-06 -0.201 0.399 — — 11 0 View 3D
STK11 Predictomes -0.054 3.78e-04 -0.153 0.424 — — 12 0 View 3D
HRAS Predictomes 0.062 3.13e-19 0.352 0.676 — — 14 0 View 3D
YWHAQ Predictomes 0.011 4.09e-01 -0.037 0.482 — — 13 0 View 3D
HRAS Predictomes 0.053 4.96e-15 0.329 0.665 — — 12 0 View 3D
KSR2 Predictomes 0.002 1.64e-01 0.058 0.529 — — 14 0 View 3D
YWHAZ Predictomes 0.029 5.21e-01 0.029 0.514 — — 13 0 View 3D
RRAS2 Predictomes 0.067 1.50e-21 0.366 0.683 — — 15 0 View 3D
BRAF Predictomes -0.040 2.53e-03 -0.127 0.437 — — 13 0 View 3D
YWHAE Predictomes 0.025 8.96e-01 0.006 0.503 — — 12 0 View 3D
YWHAG Predictomes 0.060 1.19e-01 0.083 0.542 — — 8 0 View 3D
YWHAE Predictomes 0.027 5.98e-01 0.024 0.512 — — 13 0 View 3D
YWHAG Predictomes 0.057 1.69e-01 0.074 0.537 — — 8 0 View 3D
YWHAQ Predictomes 0.029 9.53e-01 0.003 0.501 — — 12 0 View 3D
YWHAE Predictomes 0.022 9.68e-01 -0.002 0.499 — — 12 0 View 3D
MAP2K3 Predictomes -0.074 4.20e-06 -0.233 0.384 — — 8 0 View 3D
STK11 Predictomes -0.039 8.13e-03 -0.115 0.442 — — 12 0 View 3D
SFN Predictomes 0.054 2.25e-01 0.066 0.533 — — 8 0 View 3D
MAP2K1 Predictomes -0.045 1.89e-03 -0.120 0.440 — — 16 0 View 3D
RAF1 Predictomes -0.033 4.94e-02 -0.081 0.459 — — 14 0 View 3D
RRAS2 Predictomes 0.077 5.68e-22 0.378 0.689 — — 14 0 View 3D
YWHAB Predictomes 0.026 5.71e-01 0.025 0.512 — — 14 0 View 3D
KSR2 Predictomes -0.006 8.39e-01 -0.009 0.495 — — 14 0 View 3D
KRAS Predictomes 0.062 4.18e-19 0.352 0.676 — — 14 0 View 3D
SFN Predictomes 0.045 3.01e-01 0.053 0.527 — — 9 0 View 3D
NRAS Predictomes 0.062 2.84e-19 0.352 0.676 — — 14 0 View 3D
KSR1 Predictomes -0.007 7.09e-01 -0.018 0.491 — — 12 0 View 3D
YWHAZ Zhang_et_al 0.045 3.75e-03 0.189 0.595 — — 5 0 View 3D
A0A1B0GUL7 Zhang_et_al -0.063 1.34e-11 -0.241 0.380 — — 17 0 View 3D
EGFR Zhang_et_al -0.026 2.33e-02 -0.117 0.442 — — 9 0 View 3D
MAP2K2 Zhang_et_al -0.076 9.34e-17 -0.294 0.353 — — 17 0 View 3D
MAP2K1 Zhang_et_al -0.036 1.40e-02 -0.133 0.434 — — 8 0 View 3D
YWHAH Zhang_et_al 0.021 2.84e-01 0.085 0.543 — — 4 0 View 3D
RABGGTB Zhang_et_al 0.079 6.31e-10 0.310 0.655 — — 8 0 View 3D