EGFR — Abundance

🧬 View Structure

73 interactions

DMS Score Heatmap Scroll horizontally • click a column to see interactions • ■ purple strip = interface positions

TM_ErbB1 PTKc_EGFR A V I L G F Y W C M P S T N Q D E H K R * 680 700 720 740 760 780 800 820 840 860 880 900 920 940 960 980 1000 1020 1040 1060 1080 1100 1180 1200 0.50 1.00 1.50
Click a position to see interactions — ■ orange strip marks interface positions (darker = more interactions)

Significant Interactions

Interactor Predictor Log FC p-value (FDR) Cliff's Delta AUROC Unique Pos. % Unique # Interface Clashes Structure
PPIB Predictomes 0.085 2.85e-05 0.233 0.616 — — 7 0 View 3D
EGF Predictomes 0.045 2.00e-01 0.086 0.543 — — 5 0 View 3D
ERRFI1 Predictomes 0.037 9.03e-04 0.113 0.557 — — 25 0 View 3D
SGSM2 Predictomes 0.120 4.92e-06 0.329 0.664 1 25% 4 0 View 3D
EGF Predictomes 0.030 1.45e-01 0.072 0.536 — — 10 0 View 3D
ERBB2 Predictomes 0.058 1.38e-04 0.155 0.578 — — 16 0 View 3D
ERBB3 Predictomes 0.043 1.75e-04 0.136 0.568 — — 19 0 View 3D
ERRFI1 Predictomes 0.040 3.55e-04 0.122 0.561 — — 24 0 View 3D
SGSM2 Predictomes 0.091 9.49e-06 0.219 0.610 1 25% 9 0 View 3D
PPIB Predictomes 0.041 1.69e-03 0.151 0.575 — — 10 0 View 3D
PPIB Predictomes 0.087 2.44e-05 0.235 0.618 — — 7 0 View 3D
ERRFI1 Predictomes 0.048 1.09e-04 0.140 0.570 — — 22 0 View 3D
ABL1 Predictomes -0.035 1.09e-01 -0.120 0.440 — — 4 0 View 3D
LSM11 Zhang_et_al 0.228 1.40e-15 0.649 0.825 0 0% 3 0 View 3D
CTR9 Zhang_et_al 0.046 1.37e-03 0.108 0.554 — — 21 0 View 3D
BUB3 Zhang_et_al 0.036 3.32e-01 0.077 0.538 — — 4 0 View 3D
B4GALT1 Zhang_et_al 0.081 1.38e-02 0.212 0.606 — — 3 0 View 3D
CD2AP Zhang_et_al -0.010 7.00e-01 -0.023 0.489 — — 10 0 View 3D
SH2B3 Zhang_et_al -0.185 7.26e-17 -0.376 0.312 9 90% 10 0 View 3D
WDR44 Zhang_et_al 0.057 4.38e-03 0.125 0.563 — — 12 0 View 3D
NOTCH2 Zhang_et_al -0.025 2.87e-01 -0.076 0.462 4 100% 5 0 View 3D
NOTCH2 Zhang_et_al 0.105 1.44e-04 0.286 0.643 4 100% 4 0 View 3D
NOTCH2 Zhang_et_al -0.014 9.62e-01 0.002 0.501 4 100% 13 0 View 3D
PIK3R4 Zhang_et_al 0.051 3.31e-03 0.132 0.566 — — 11 0 View 3D
IARS1 Zhang_et_al 0.040 5.38e-02 0.084 0.542 — — 13 0 View 3D
EPS15 Zhang_et_al 0.106 7.73e-09 0.285 0.642 4 44% 9 0 View 3D
LRIG3 Zhang_et_al 0.081 7.54e-05 0.223 0.611 — — 7 0 View 3D
ADAMTS9 Zhang_et_al 0.058 1.22e-04 0.164 0.582 — — 12 0 View 3D
ADAMTS9 Zhang_et_al -0.012 6.91e-01 -0.030 0.485 — — 6 0 View 3D
ITGB2 Zhang_et_al 0.060 1.26e-03 0.167 0.583 — — 9 0 View 3D
MYO9A Zhang_et_al 0.061 3.17e-03 0.153 0.577 — — 9 0 View 3D
CTNNB1 Zhang_et_al 0.090 5.65e-04 0.249 0.624 — — 4 0 View 3D
CRKL Zhang_et_al -0.012 4.68e-01 -0.070 0.465 — — 3 0 View 3D
ITGA2B Zhang_et_al 0.022 7.75e-01 0.019 0.509 — — 8 0 View 3D
KAT7 Zhang_et_al 0.049 5.78e-03 0.138 0.569 — — 9 0 View 3D
PLAA Zhang_et_al 0.038 4.50e-01 0.063 0.532 — — 4 0 View 3D
CLP1 Zhang_et_al 0.059 2.45e-04 0.163 0.581 — — 11 0 View 3D
ATP6V1H Zhang_et_al 0.010 9.13e-01 -0.009 0.495 — — 4 0 View 3D
CBLC Zhang_et_al 0.110 9.67e-08 0.335 0.668 4 80% 5 0 View 3D
FERMT1 Zhang_et_al 0.116 3.09e-09 0.344 0.672 3 50% 6 0 View 3D
ARAF Zhang_et_al 0.092 7.15e-06 0.251 0.625 — — 7 0 View 3D
MLST8 Zhang_et_al -0.002 8.30e-01 -0.019 0.490 — — 4 0 View 3D
VAV2 Zhang_et_al -0.159 3.44e-06 -0.333 0.333 3 75% 4 0 View 3D
LRIG1 Zhang_et_al 0.073 4.35e-04 0.186 0.593 — — 8 0 View 3D
SOS1 Zhang_et_al 0.020 9.54e-02 0.087 0.544 — — 9 0 View 3D
GATB Zhang_et_al 0.116 5.87e-10 0.357 0.679 3 50% 6 0 View 3D
TWF1 Zhang_et_al -0.040 3.97e-01 -0.085 0.457 — — 3 0 View 3D
SOS2 Zhang_et_al 0.074 1.71e-02 0.179 0.590 — — 4 0 View 3D
SOS2 Zhang_et_al 0.058 1.35e-02 0.137 0.569 — — 8 0 View 3D
CHIA Zhang_et_al 0.024 4.82e-01 0.047 0.524 — — 6 0 View 3D
EED Zhang_et_al 0.097 6.44e-04 0.287 0.643 — — 3 0 View 3D
ACOT9 Zhang_et_al 0.033 2.54e-01 0.075 0.537 — — 6 0 View 3D
JPH1 Zhang_et_al 0.009 8.37e-01 -0.013 0.493 — — 7 0 View 3D
ANKRD13A Zhang_et_al 0.063 1.19e-02 0.135 0.568 — — 8 0 View 3D
SEL1L Zhang_et_al 0.054 6.23e-03 0.136 0.568 — — 10 0 View 3D
NCK1 Zhang_et_al 0.105 4.21e-04 0.300 0.650 1 33% 3 0 View 3D
JUP Zhang_et_al 0.016 8.67e-01 0.010 0.505 — — 9 0 View 3D
MIOS Zhang_et_al 0.068 9.15e-04 0.203 0.601 — — 6 0 View 3D
CTNND1 Zhang_et_al 0.036 2.08e-01 0.071 0.536 — — 8 0 View 3D
PTPRF Zhang_et_al -0.036 5.98e-02 -0.128 0.436 — — 5 0 View 3D
EGFR RCSB_PDB -0.015 4.09e-01 -0.040 0.480 — — 11 0 View 3D
EGFR RCSB_PDB 0.018 3.33e-01 0.044 0.522 — — 12 0 View 3D
ERRFI1 RCSB_PDB 0.038 2.69e-04 0.123 0.562 — — 23 0 View 3D
ERBB3 RCSB_PDB 0.067 3.90e-11 0.225 0.613 — — 20 0 View 3D
EGFR RCSB_PDB -0.011 5.08e-01 -0.032 0.484 — — 11 0 View 3D
EGFR RCSB_PDB -0.008 5.71e-01 -0.027 0.486 — — 11 0 View 3D
ERBB3 RCSB_PDB 0.065 1.58e-09 0.199 0.599 — — 22 0 View 3D
ERBB3 RCSB_PDB 0.059 4.42e-08 0.187 0.594 — — 20 0 View 3D
EGFR RCSB_PDB -0.099 6.63e-03 -0.193 0.404 — — 4 0 View 3D
EGFR RCSB_PDB -0.008 5.66e-01 -0.027 0.487 — — 12 0 View 3D
EGFR RCSB_PDB -0.000 8.62e-01 -0.009 0.496 — — 11 0 View 3D
EGFR RCSB_PDB -0.090 1.56e-02 -0.173 0.413 — — 4 0 View 3D
ERRFI1 RCSB_PDB 0.081 1.49e-06 0.202 0.601 — — 13 0 View 3D