KSR2 — Abundance

🧬 View Structure

23 interactions

DMS Score Heatmap Scroll horizontally • click a column to see interactions • ■ purple strip = interface positions

PK_KSR2 A V I L G F Y W C M P S T N Q D E H K R * 500 520 540 560 580 600 620 640 660 680 700 720 740 760 780 800 820 840 860 880 900 920 940 0.48 1.00 1.50
Click a position to see interactions — ■ orange strip marks interface positions (darker = more interactions)

Significant Interactions

Interactor Predictor Log FC p-value (FDR) Cliff's Delta AUROC Unique Pos. % Unique # Interface Clashes Structure
SOX2 Predictomes 0.161 3.06e-12 0.481 0.740 0 0% 4 0 View 3D
PRKAA1 Predictomes 0.184 4.32e-09 0.569 0.785 11 69% 16 0 View 3D
MAP2K1 Predictomes -0.172 5.55e-40 -0.486 0.257 0 0% 16 0 View 3D
MAP2K2 Predictomes -0.172 1.80e-41 -0.484 0.258 1 6% 17 0 View 3D
MAP2K2 Predictomes -0.176 6.51e-42 -0.500 0.250 1 6% 16 0 View 3D
SOX2 Predictomes 0.156 1.33e-11 0.467 0.734 0 0% 5 0 View 3D
BRAF Predictomes 0.123 7.22e-12 0.324 0.662 1 5% 19 0 View 3D
RAF1 Predictomes 0.103 3.59e-09 0.280 0.640 0 0% 9 0 View 3D
SOX2 Predictomes 0.165 2.58e-17 0.480 0.740 0 0% 6 0 View 3D
PRKAA1 Predictomes 0.230 2.35e-11 0.647 0.823 11 69% 14 0 View 3D
BRAF Predictomes 0.107 4.67e-10 0.283 0.642 1 5% 20 0 View 3D
PRKAA1 Predictomes 0.019 9.92e-01 -0.001 0.499 11 69% 7 0 View 3D
MAP2K1 Predictomes -0.178 3.86e-43 -0.507 0.247 0 0% 16 0 View 3D
ARAF Predictomes 0.109 2.26e-10 0.288 0.644 1 7% 14 0 View 3D
KSR1 Predictomes 0.124 5.31e-13 0.342 0.671 0 0% 18 0 View 3D
MAP2K1 Predictomes -0.168 1.40e-38 -0.478 0.261 0 0% 16 0 View 3D
KSR1 Predictomes 0.129 2.34e-17 0.353 0.677 0 0% 20 0 View 3D
ARAF Predictomes 0.120 1.19e-13 0.321 0.660 1 7% 15 0 View 3D
RAF1 Predictomes 0.117 7.85e-12 0.309 0.655 0 0% 13 0 View 3D
KSR1 Predictomes 0.116 1.36e-11 0.320 0.660 0 0% 17 0 View 3D
MAP2K2 Predictomes -0.158 7.60e-36 -0.449 0.275 1 6% 17 0 View 3D
FBXL2 Zhang_et_al 0.044 4.72e-02 0.149 0.575 — — 4 0 View 3D
BRAF Zhang_et_al 0.116 4.42e-13 0.318 0.659 0 0% 11 0 View 3D