KSR2 — Activity

🧬 View Structure

25 interactions

DMS Score Heatmap Scroll horizontally • click a column to see interactions • ■ purple strip = interface positions

SAM_KSR1_N SAM_KSR1 superfamily C1 superfamily PK_KSR2 A V I L G F Y W C M P S T N Q D E H K R * 20 40 60 80 100 120 140 160 180 200 220 240 260 280 300 320 340 360 380 400 420 440 460 480 500 520 540 560 580 600 620 640 660 680 700 720 740 760 780 800 820 840 860 880 900 920 940 0.50 1.00 2.10
Click a position to see interactions — ■ orange strip marks interface positions (darker = more interactions)

Significant Interactions

Interactor Predictor Log FC p-value (FDR) Cliff's Delta AUROC Unique Pos. % Unique # Interface Clashes Structure
SOX2 Predictomes -0.455 3.41e-06 -0.545 0.228 0 0% 4 0 View 3D
PRKAA1 Predictomes -0.330 1.34e-25 -0.392 0.304 11 69% 16 0 View 3D
MAP2K1 Predictomes 0.438 4.94e-40 0.603 0.801 0 0% 16 0 View 3D
MAP2K2 Predictomes 0.437 1.92e-41 0.599 0.800 1 6% 17 0 View 3D
MAP2K2 Predictomes 0.434 1.37e-39 0.600 0.800 1 6% 16 0 View 3D
SOX2 Predictomes -0.411 1.03e-09 -0.543 0.229 0 0% 5 0 View 3D
BRAF Predictomes -0.315 3.74e-24 -0.404 0.298 1 5% 19 0 View 3D
RAF1 Predictomes -0.097 1.42e-01 -0.122 0.439 1 8% 9 0 View 3D
SOX2 Predictomes -0.426 3.36e-07 -0.516 0.242 0 0% 6 0 View 3D
PRKAA1 Predictomes -0.329 2.29e-20 -0.372 0.314 11 69% 14 0 View 3D
BRAF Predictomes -0.325 9.06e-26 -0.415 0.292 1 5% 20 0 View 3D
PRKAA1 Predictomes -0.226 5.45e-04 -0.205 0.397 11 69% 7 0 View 3D
MAP2K1 Predictomes 0.450 3.36e-42 0.619 0.809 0 0% 16 0 View 3D
ARAF Predictomes -0.230 1.31e-06 -0.252 0.374 1 7% 14 0 View 3D
KSR1 Predictomes -0.328 8.56e-25 -0.426 0.287 0 0% 18 0 View 3D
MAP2K1 Predictomes 0.435 5.40e-40 0.603 0.801 0 0% 16 0 View 3D
KSR1 Predictomes -0.300 8.73e-24 -0.413 0.293 0 0% 20 0 View 3D
ARAF Predictomes -0.250 3.60e-09 -0.300 0.350 1 7% 15 0 View 3D
RAF1 Predictomes -0.276 1.69e-11 -0.375 0.312 1 8% 13 0 View 3D
KSR1 Predictomes -0.295 9.36e-22 -0.410 0.295 0 0% 17 0 View 3D
MAP2K2 Predictomes 0.409 3.97e-37 0.565 0.783 1 6% 17 0 View 3D
CDC27 Zhang_et_al -0.012 8.80e-01 0.012 0.506 — — 5 0 View 3D
FBXL2 Zhang_et_al -0.633 6.87e-13 -0.738 0.131 4 100% 4 0 View 3D
BRAF Zhang_et_al -0.091 4.16e-06 -0.230 0.385 0 0% 10 0 View 3D
BRAF Zhang_et_al -0.275 2.52e-05 -0.313 0.344 0 0% 11 0 View 3D