KSR2 — Abundance_hsp90i

🧬 View Structure

23 interactions

DMS Score Heatmap Scroll horizontally • click a column to see interactions • ■ purple strip = interface positions

PK_KSR2 A V I L G F Y W C M P S T N Q D E H K R * 500 520 540 560 580 600 620 640 660 680 700 720 740 760 780 800 820 840 860 880 900 920 940 0.50 1.00 1.50
Click a position to see interactions — ■ orange strip marks interface positions (darker = more interactions)

Significant Interactions

Interactor Predictor Log FC p-value (FDR) Cliff's Delta AUROC Unique Pos. % Unique # Interface Clashes Structure
SOX2 Predictomes 0.179 4.41e-10 0.431 0.715 0 0% 4 0 View 3D
PRKAA1 Predictomes 0.194 4.00e-08 0.533 0.767 11 69% 16 0 View 3D
MAP2K1 Predictomes -0.166 2.10e-34 -0.449 0.275 0 0% 16 0 View 3D
MAP2K2 Predictomes -0.157 1.41e-32 -0.426 0.287 1 6% 17 0 View 3D
MAP2K2 Predictomes -0.168 8.04e-36 -0.460 0.270 1 6% 16 0 View 3D
SOX2 Predictomes 0.171 2.95e-09 0.411 0.705 0 0% 5 0 View 3D
BRAF Predictomes 0.106 5.57e-08 0.258 0.629 1 5% 19 0 View 3D
RAF1 Predictomes 0.091 3.88e-06 0.221 0.610 — — 9 0 View 3D
SOX2 Predictomes 0.143 5.79e-10 0.355 0.677 0 0% 6 0 View 3D
PRKAA1 Predictomes 0.261 2.77e-11 0.644 0.822 11 69% 14 0 View 3D
BRAF Predictomes 0.090 1.91e-06 0.218 0.609 1 5% 20 0 View 3D
PRKAA1 Predictomes -0.054 1.63e-01 -0.145 0.428 11 69% 7 0 View 3D
MAP2K1 Predictomes -0.168 3.11e-35 -0.455 0.272 0 0% 16 0 View 3D
ARAF Predictomes 0.093 6.64e-07 0.227 0.613 0 0% 14 0 View 3D
KSR1 Predictomes 0.132 1.13e-10 0.306 0.653 1 6% 18 0 View 3D
MAP2K1 Predictomes -0.162 8.35e-34 -0.446 0.277 0 0% 16 0 View 3D
KSR1 Predictomes 0.132 1.17e-14 0.322 0.661 1 6% 20 0 View 3D
ARAF Predictomes 0.118 1.00e-10 0.280 0.640 0 0% 15 0 View 3D
RAF1 Predictomes 0.099 6.92e-08 0.245 0.623 — — 13 0 View 3D
KSR1 Predictomes 0.122 2.62e-09 0.283 0.641 1 6% 17 0 View 3D
MAP2K2 Predictomes -0.154 3.65e-31 -0.417 0.291 1 6% 17 0 View 3D
FBXL2 Zhang_et_al 0.024 2.21e-01 0.096 0.548 — — 4 0 View 3D
BRAF Zhang_et_al 0.100 1.10e-08 0.253 0.627 — — 11 0 View 3D