RET — Abundance

🧬 View Structure

20 interactions

DMS Score Heatmap Scroll horizontally • click a column to see interactions • ■ purple strip = interface positions

PTKc_RET A V I L G F Y W C M P S T N Q D E H K R * 660 680 700 720 740 760 780 800 820 840 860 880 900 920 940 960 980 1000 1020 1040 1060 1080 1100 0.50 1.00 1.50
Click a position to see interactions — ■ orange strip marks interface positions (darker = more interactions)

Significant Interactions

Interactor Predictor Log FC p-value (FDR) Cliff's Delta AUROC Unique Pos. % Unique # Interface Clashes Structure
GFRA1 Predictomes -0.042 2.01e-01 -0.094 0.453 — — 4 0 View 3D
PLCG1 Predictomes -0.122 6.06e-13 -0.359 0.320 8 100% 8 0 View 3D
PLCG1 Predictomes -0.120 1.16e-13 -0.353 0.323 8 100% 9 0 View 3D
NTRK1 Predictomes -0.061 1.57e-02 -0.201 0.400 — — 3 0 View 3D
SORL1 Zhang_et_al -0.042 8.86e-02 -0.095 0.453 — — 8 0 View 3D
SORL1 Zhang_et_al 0.007 5.69e-01 -0.038 0.481 — — 7 0 View 3D
PTPRA Zhang_et_al 0.076 3.88e-03 0.190 0.595 — — 5 0 View 3D
GNPTAB Zhang_et_al -0.025 2.73e-01 -0.062 0.469 — — 8 0 View 3D
RAPH1 Zhang_et_al -0.021 6.82e-01 -0.030 0.485 — — 6 0 View 3D
CBLC Zhang_et_al -0.027 2.20e-01 -0.095 0.452 — — 4 0 View 3D
RET RCSB_PDB 0.103 5.34e-22 0.316 0.658 21 100% 21 0 View 3D
RET RCSB_PDB 0.112 2.05e-23 0.333 0.667 21 100% 20 0 View 3D
RET RCSB_PDB 0.103 5.95e-23 0.316 0.658 21 100% 22 0 View 3D
RET RCSB_PDB 0.113 7.07e-25 0.333 0.666 21 100% 22 0 View 3D
RET RCSB_PDB 0.094 2.86e-17 0.283 0.642 21 100% 20 0 View 3D
RET RCSB_PDB 0.105 5.15e-19 0.310 0.655 21 100% 18 0 View 3D
RET RCSB_PDB 0.091 2.39e-17 0.283 0.642 21 100% 20 0 View 3D
RET RCSB_PDB 0.098 2.89e-20 0.302 0.651 21 100% 21 0 View 3D
RET RCSB_PDB 0.099 2.10e-18 0.298 0.649 21 100% 19 0 View 3D
RET RCSB_PDB 0.097 8.71e-17 0.290 0.645 21 100% 18 0 View 3D