RET — Abundance_hsp90i

🧬 View Structure

20 interactions

DMS Score Heatmap Scroll horizontally • click a column to see interactions • ■ purple strip = interface positions

PTKc_RET A V I L G F Y W C M P S T N Q D E H K R * 660 680 700 720 740 760 780 800 820 840 860 880 900 920 940 960 980 1000 1020 1040 1060 1080 1100 0.50 1.00 1.50
Click a position to see interactions — ■ orange strip marks interface positions (darker = more interactions)

Significant Interactions

Interactor Predictor Log FC p-value (FDR) Cliff's Delta AUROC Unique Pos. % Unique # Interface Clashes Structure
GFRA1 Predictomes -0.005 8.83e-01 -0.011 0.494 — — 4 0 View 3D
PLCG1 Predictomes -0.157 9.83e-16 -0.400 0.300 8 100% 8 0 View 3D
PLCG1 Predictomes -0.147 3.14e-15 -0.375 0.313 8 100% 9 0 View 3D
NTRK1 Predictomes -0.073 5.86e-03 -0.228 0.386 — — 3 0 View 3D
SORL1 Zhang_et_al -0.060 4.51e-03 -0.151 0.424 — — 8 0 View 3D
SORL1 Zhang_et_al -0.011 6.95e-01 -0.027 0.487 — — 7 0 View 3D
PTPRA Zhang_et_al 0.099 9.10e-06 0.284 0.642 — — 5 0 View 3D
GNPTAB Zhang_et_al 0.066 5.21e-05 0.206 0.603 — — 8 0 View 3D
RAPH1 Zhang_et_al 0.033 1.02e-01 0.103 0.551 — — 6 0 View 3D
CBLC Zhang_et_al 0.042 4.69e-02 0.148 0.574 — — 4 0 View 3D
RET RCSB_PDB 0.122 2.67e-25 0.340 0.670 21 100% 21 0 View 3D
RET RCSB_PDB 0.125 7.02e-23 0.329 0.664 21 100% 20 0 View 3D
RET RCSB_PDB 0.124 2.41e-24 0.326 0.663 21 100% 22 0 View 3D
RET RCSB_PDB 0.110 3.33e-19 0.290 0.645 21 100% 22 0 View 3D
RET RCSB_PDB 0.125 2.66e-24 0.340 0.670 21 100% 20 0 View 3D
RET RCSB_PDB 0.115 3.91e-19 0.311 0.656 21 100% 18 0 View 3D
RET RCSB_PDB 0.124 4.41e-23 0.330 0.665 21 100% 20 0 View 3D
RET RCSB_PDB 0.110 1.34e-19 0.297 0.648 21 100% 21 0 View 3D
RET RCSB_PDB 0.122 2.29e-22 0.331 0.666 21 100% 19 0 View 3D
RET RCSB_PDB 0.105 8.47e-16 0.281 0.640 21 100% 18 0 View 3D